Formoterol alternatives: what works and when
Formoterol is a long-acting beta2-agonist (LABA) many people use for asthma or COPD. If you're looking for alternatives — because of side effects, cost, availability, or a doctor’s suggestion — there are clear options. Below I’ll cover the main drug classes, a few specific medicines, and simple rules to help you talk with your clinician.
Other LABAs and combo inhalers
If you like formoterol’s long action, try other LABAs. Salmeterol works similarly but starts working slower (often 15–20 minutes). Vilanterol, indacaterol, and olodaterol are other long-acting choices used for COPD and sometimes in combos for asthma. Many of these come combined with an inhaled steroid — for example, salmeterol+fluticasone or vilanterol+fluticasone furoate. Those combos cut flare-ups more than a LABA alone in asthma.
Quick comparison:
- Formoterol — fast onset, 12-hour effect.
- Salmeterol — slower onset, similar duration.
- Vilanterol/Indacaterol/Olodaterol — long action, used mostly in COPD or fixed combos.
Non-LABA options and rescue meds
If you need different action or fewer side effects, try a LAMA (long-acting muscarinic antagonist) such as tiotropium, aclidinium, or glycopyrronium. LAMAs relax airways differently and are often used for COPD; doctors sometimes combine a LABA plus a LAMA for better control. For quick relief of symptoms, short-acting beta agonists (SABA) like albuterol (salbutamol) or levalbuterol are still the go-to rescue inhalers.
Also think about inhaled corticosteroids (budesonide, fluticasone, beclomethasone). For asthma, LABAs should usually be paired with an inhaled steroid. Using a LABA alone for asthma can increase risk of severe attacks — always follow your doctor's plan.
Beyond medicines, small changes help a lot: stop smoking, get flu and pneumonia shots if recommended, use a spacer with metered-dose inhalers, and consider pulmonary rehab for COPD. These steps can reduce symptoms and make any inhaler work better.
How to pick one? Consider how fast you need relief (formoterol is fast), what side effects you had, cost, and whether you need steroid coverage too. If you’re switching because of availability, ask your pharmacist about equivalent combos or a temporary replacement. If side effects like tremor or palpitations show up, tell your provider — a different class may fit better.
Want a tailored switch? Talk to your doctor or pharmacist with these points: your diagnosis (asthma vs COPD), current inhaler type and dose, symptom pattern, and any past reactions. They can recommend a safe alternative and show you the right inhaler technique so the new medicine actually helps.
Always follow medical advice — this guide is practical info, not personalized medical care. If symptoms worsen after a change, contact your healthcare provider right away.

Formoterol Alternatives: Once-Daily Long-Acting Bronchodilators Compared
Martyn F. May. 3 0Wondering if formoterol is truly the optimal option for managing asthma or COPD? This article gets into the nitty-gritty of once-daily bronchodilators that promise real competition for formoterol’s duration and convenience. We’ll size up other medications on the market, spotlight clinical data, insider tips, and practical details for patients and physicians. Readers can expect a deep dive into dosing, device types, safety, and the future of inhaler therapy. If you’re considering shifting from formoterol—or just want to see what new alternatives offer—this guide has you covered.
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