Stromectol alternatives: what to use instead of ivermectin

If your doctor says Stromectol (ivermectin) isn't right for you, there are several good alternatives—each targets certain parasites better than others. The trick is matching the drug to the bug and your health situation. Below I’ll break down common replacements, why they’re chosen, and how to stay safe when switching treatments.

Match the drug to the parasite

Not every antiparasitic treats every infection. Here are common alternatives and when they’re used:

Mebendazole (Vermox) — Often used for pinworms, roundworms, and some intestinal parasites. It’s a go-to for simple worm infections and works well for most household outbreaks.

Albendazole — Favored for tapeworms, certain roundworms, and more serious infections like neurocysticercosis and hydatid disease. Doctors pick albendazole when tissue-invasive parasites are involved.

Praziquantel — Best for schistosomiasis and many tapeworms. It’s the main option for blood flukes and some liver fluke infections.

Pyrantel pamoate — A safe over-the-counter option in many countries for pinworms and hookworms. It’s often used in children and for quick household treatment.

Nitazoxanide — Useful for protozoal infections such as Giardia and Cryptosporidium. It’s sometimes chosen when common antibiotics or antiparasitics don’t help.

Diethylcarbamazine (DEC) — Used mainly for filarial infections like lymphatic filariasis. It’s not a general-purpose drug and needs medical supervision.

Topicals (permethrin, crotamiton) — For skin parasites like scabies or lice, creams and lotions work better than oral meds.

How to pick safely

First, confirm the diagnosis. A stool test, blood test, or skin exam changes which drug is best. Second, tell your provider about pregnancy, breastfeeding, liver disease, and other meds—these affect safety. For example, some drugs are avoided in pregnancy or need dose changes with liver problems.

Avoid self-medicating with online sources of uncertain quality. Get a prescription from a trusted clinician and use a licensed pharmacy. If you see treatments online claiming to cure everything, that’s a red flag.

Watch for side effects: common ones are stomach upset, dizziness, or mild rashes. Serious reactions are rare but can happen; if you feel severe weakness, vision changes, high fever, or worsening neurological signs, get medical help right away.

Finally, follow follow-up advice. Some infections need repeat testing to confirm the parasite is gone. Household contacts may need treatment too, and sometimes simple hygiene steps—washing bedding, hand hygiene—prevent re-infection.

If you’re unsure which alternative fits your situation, bring test results and notes on symptoms to your clinician. A targeted choice beats guessing—and keeps you safer and better faster.