Stromectol replacement: what to use instead of ivermectin

Need an alternative to Stromectol (ivermectin)? Choice depends on the infection. Ivermectin treats several parasites well, but other drugs work better for some conditions or for people who can’t take ivermectin. This guide explains common replacements, when they’re used, and how to stay safe.

Common drug alternatives by condition

For intestinal worms (like roundworms or hookworms) doctors often use albendazole or mebendazole (brand name Vermox). These are broad-spectrum antiparasitics taken orally and work for many gut parasites. For pinworm (Enterobius), mebendazole is a common first choice.

Strongyloides stercoralis is usually best treated with ivermectin, but albendazole has been used when ivermectin isn’t available—though it’s generally less effective. Thiabendazole used to be common for some infections but now is less favored because of side effects.

For scabies, topical permethrin 5% cream is the most common non-ivermectin option. Apply it to the whole body as directed by your healthcare provider. Crotamiton and sulfur ointments are alternatives when permethrin can’t be used.

Onchocerciasis (river blindness) historically used repeated ivermectin doses, but doxycycline is sometimes used to target the bacteria (Wolbachia) that help the parasite survive. That approach requires longer treatment and a doctor’s supervision.

How to pick the right replacement

Match the drug to the parasite and to your health: pregnancy, breastfeeding, liver disease, age, and other meds all matter. For example, some antiparasitics aren’t recommended in pregnancy. Share your full medical history with the prescriber so they can pick the safest option and dose.

Resistance and local guidelines matter. In some places albendazole resistance is rising for certain parasites, so doctors choose the drug based on local patterns and test results when available.

Side effects vary. Albendazole and mebendazole can cause stomach upset, headache, or temporary liver changes. Topical permethrin can irritate skin. Serious reactions are rare but possible—report new symptoms to your provider quickly.

Buy meds only from licensed pharmacies. Prescription drugs should be prescribed by a clinician who evaluated you. Avoid unverified online sellers and using ivermectin intended for animals—formulation and dosing differ and can be dangerous.

If you suspect an infection, get tested when possible. Tests help confirm which parasite is present and guide the best drug choice. When treatment starts, follow dosing and follow-up instructions closely. If symptoms don’t improve or you notice side effects, contact your doctor right away.

Want help finding an option? Ask your pharmacist or clinician about albendazole, mebendazole, permethrin, or doxycycline depending on your diagnosis. They’ll explain benefits, risks, and the correct dose for you.